Renal (Kidney) Cells
The kidney contains many different types of cells including, but not limited to, podocytes, proximal and distal tubule cells, duct cells, segment cells and interstitial cells. Most of these renal cell types can be isolated from fresh organs and cultured in vitro. However, in most cases, they proliferation potential and ability is limited.
Nevertheless, many renal cell types exhibit a high metabolic rate enabling their function to be assessed using metabolic viability assays. For renal toxicity studies, Preferred Cell Systems™ has developed RenalGlo-Tox HT.
In addition to primary explanted renal cells, there are many renal cell lines that can be used for renal research and Preferred Cell Systems™ has built assay platforms that can be used for both primary and renal cell lines. As for other cell types, Preferred Cell Systems™ has developed these tools so that any available plate reader can be used. Some renal cells require adhesion to grow, while others may grow under non-adherent culture conditions. For this reason, the following assays are available with non-adherent or adherent, 96-well plates, included.
- RenalGLO™ using a bioluminescence readout.
- RenalFLUOR™ using a fluorescence readout.
- RenalLIGHT™ using an absorbance/colorimetric readout.
These assays provide the flexibility for the investigator to use their own growth medium and culture protocols.
Please contact Preferred Cell Systems™ for more information at email@example.com or call (719) 264-6251.