CRUXRUFA™ - Human Platelet Lysate
A Supplement to Expand and Maintain Mesenchymal Stem Cells (MSC)
and Other Cell Types Without the Need for Fetal Bovine Serum (FBS)
Benefits of Using CRUXRUFA™-Human Platelet Lysate
- A xeno-free alternative to fetal bovine serum (FBS) and bovine serum albumin (BSA)
- For the expansion and maintenance of MSC/MPC and other cell types
- Consistently high intra- and inter-batch quality. MSC/MPC proliferation quality performance of CRUXRUFA HPL is carried out by HemoGenix® using its MSCGlo™-96 HuQC assay platform.
- Produced in Germany by the Red Cross Blood Bank
- Rich in growth factors and cytokines
- Use at 10% v/v culture volume or less
The graph shows a comparison between CRUXRUFA™ HPL Research and CRUXRUFA™ HPL FD GMP with a well-known competitor human platelet lysate and MSCGro Low Serum, used as a control. Mesenchymal stem/progenitor cells (MSC/MPC) were cultured in 96-well plates at different cell concentrations in the presence of 10% HPL. MSC/MPC proliferation was measured using the Preferred Cell Systems™ MSCGlo™ QC ATP bioluminescence assay. The results indicate that the CRUXRUFA™ Human Platelet Lysate, fibronogen-free GMP formulation produces statistically better results than another competitor brand.
All CRUXRUFA™ GMP grade formulations are manufactured under strict Good Manufacturing Procedures (GMP).
CRUXRUFA™ GMP Q formulations represent the highest safety quality available due to quarantine storage according to German hemotherapy guidelines (188.8.131.52) for therapeutic single-donor plasma. All donors used for this quality HPL have undergone and passed serology and NAT-testing for blood-transmissible infectious diseases for at least 4 months after a platelet donation.
CRUXRUFA™ FD is fibrinogen-depleted human platelet lysate. No additional anticoagulants (e.g. heparin) are necessary. As shown in the graph, CRUXRUFA FD products demonstrate the greatest stimulation potential of all human platelet lysates.
When ordering CRUXRUFA™ Human Platelet Lysate, simply click on Catalog Numberin the table below and you will be taken directly to the desired product.
|CRUXRUFA™ HPL Research||M-CR-50||Research||50mL|
|CRUXRUFA™ HPL GMP||M-CRGP-50||GMP grade||50mL|
|CRUXRUFA™ HPL GMP Q||M-CRGPQ-50||GMP Quarantine||50mL|
|CRUXRUFA™ HPL FD GMP||M-CRGPFD-50||GMP Fibrinogen-free||50mL|
|CRUXRUFA™ HPL FD GMP Q||M-CRGPFDQ-50||GMP Fibrinogeno-free Quarantine||50mL|
Larger quantities are also available.